Prick a Finger and Save a Life: How YOU Can Make a Difference in Celiac Disease Research

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Prick a Finger and Save a Life: How YOU Can Make a Difference in Celiac Disease Research
It’s just like being a little kid with a super sore throat and your mom taking you to the doctor to get a test for strep throat. The doctor swabs your throat with two sticks to find out what nasty bacteria is camping out. In just moments you’ve got a diagnosis of strep throat and […]
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Is There a Connection Between Antibiotic Use and Celiac Disease Autoimmunity?

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Is There a Connection Between Antibiotic Use and Celiac Disease Autoimmunity?
Researchers still don’t have much good data on the consequences of antibiotic use in early life and how that relates to the risk of certain autoimmune diseases. A team of researchers recently set out to test the association between early-life antibiotic use and islet or celiac disease autoimmunity in genetically at-risk children prospectively followed up […]
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Sjögren's Syndrome: The Link with Celiac Disease

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Sjögren's Syndrome: The Link with Celiac Disease
What is the link between the autoimmune diseases Sjögren’s syndrome and celiac disease? In a study, 14.7% of Sjögren’s syndrome patients were found to have celiac disease and 11.8% of non-celiac Sjögren’s syndrome patients were found to have inflamed mucosa in the small intestine. With this knowledge, people who suffer from Sjögren’s syndrome may be […]
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Are Doctors Missing 90% of Celiac Disease Cases?

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Are Doctors Missing 90% of Celiac Disease Cases?
Are doctors even getting close to diagnosing the actual number of cases of celiac disease? Or are they missing the vast majority? Researchers have said for some time that there are far more people with celiac disease than are being diagnosed, and that the vast majority of cases go undiagnosed. If a new study by […]
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Could the Dual Activation of IRF1 and IRF1-Regulated Genes Be a Key to Celiac Disease Symptoms?

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Could the Dual Activation of IRF1 and IRF1-Regulated Genes Be a Key to Celiac Disease Symptoms?
A new study shows that activation of IRF1 and IRF1-regulated genes together, both directly and via the interleukin-18 dependent inflammasome, would greatly increase the severity of the inflammatory response. Celiac disease is a chronic inflammatory disease of the small intestine mucosa due to permanent intolerance to dietary gluten. A team of researchers recently set out to […]
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Can Undetectable Negative Tissue Transglutaminase IgA antibodies Predict Mucosal Healing in Treated Celiac Disease Patients?

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Can Undetectable Negative Tissue Transglutaminase IgA antibodies Predict Mucosal Healing in Treated Celiac Disease Patients?
Tissue transglutaminase (tTG) immunoglobulin A (IgA) testing is a sensitive adjunct to the diagnosis of coeliac disease. The threshold for positivity was developed for diagnosis, with negative results reported as below the reference value (<4 U/mL). A team of researchers recently set out to investigate if an undetectable tissue transglutaminase IgA antibodies (tTG IgA<1.2 U/mL) […]
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Is Celiac Disease at the Heart of Lawsuit Against Merrill Lynch?

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Is Celiac Disease at the Heart of Lawsuit Against Merrill Lynch?
A Merrill Lynch broker in Denver has sued the firm in federal court, claiming that its systemic “sabotage” of his relationship with clients during and following two medical leaves have cost him hundreds of thousands of dollars. In a case filed this summer in federal court in Colorado, Kirk Kringel, a broker with Merrill since 2010, alleges […]
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Do Adolescents with Celiac Disease Face Higher Cardiovascular Risk?

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Do Adolescents with Celiac Disease Face Higher Cardiovascular Risk?
Recent data show that more adults with celiac disease may face a higher risk for cardiovascular disease compared with the general population. A team of researchers recently set out to investigate the association of with cardiovascular disease risk factors at late adolescence in a cross-sectional population-based study.
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Is India the Next Frontier for Understanding Celiac Disease?

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Is India the Next Frontier for Understanding Celiac Disease?
Celiac Disease is a global disease and affects almost 0.7% of the world’s population. In India, researchers estimate that celiac disease affects about six to eight million Indians. Rates in the north India community are 1 in 100. In a bid to discuss and explore the best ways to address the challenges faced by patients […]
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Can Science Take the Guesswork Out of Diagnosing Seronegative Celiac Disease?

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Can Science Take the Guesswork Out of Diagnosing Seronegative Celiac Disease?
Patients who have clinical, genetic and histological signs of celiac disease, but no serological markers, present a challenge when it comes to making a diagnosis. If the patient doesn’t have elevated antibodies, what signs do doctors look for? What’s the best way to evaluate the patient’s natural history and response to a gluten-free diet? A […]
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Is Effective Enzyme Therapy for Celiac Disease Just Around The Corner?

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Is Effective Enzyme Therapy for Celiac Disease Just Around The Corner?
Enzyme Latiglutenase improves symptoms in some celiac patients, but which ones? Enzymes have shown some promise for treating celiac symptoms, but so far none has to improve histology or symptoms in celiac patients. There are currently several efforts underway to develop successful commercial enzyme treatments for celiac disease. Efforts include looking at the digestive enzymes in […]
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Are Doctors Following Current Biopsy Guidelines When Diagnosing Celiac Disease?

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Are Doctors Following Current Biopsy Guidelines When Diagnosing Celiac Disease?
How tightly are doctors following current guidelines for diagnosing celiac disease? Current guidelines by the British Society of Gastroenterology recommend that doctors take at least four duodenal biopsy specimens at the time of upper gastrointestinal (UGI) endoscopy when looking for celiac disease. The practice has been shown to increase celiac diagnoses, and to reduced missed […]
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Are Intestinal Worms the Future of Autoimmune Disease Treatment?

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Are Intestinal Worms the Future of Autoimmune Disease Treatment?
Long ignored and dismissed as unscientific and crude, are intestinal worms destined to be the future of autoimmune disease treatments? Hookworms. Intestinal parasites. They sound gross. The thought of having one’s gut infected with a parasitic worm generally makes people’s skin crawl. Indeed, intestinal worms, like hookworm, have a bad reputation among health experts, and […]
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Do Early Respiratory Infections Increase Risk for Celiac Disease?

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Do Early Respiratory Infections Increase Risk for Celiac Disease?
Many researchers feel that the rising number of celiac disease cases supports the idea that common infections prior to the onset of autoimmune diseases could play a role in triggering the immune response. Do more respiratory infections in childhood mean a greater likelihood of celiac disease later in life? To answer that question, a team […]
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Is This the Beginning of the End for Celiac Disease? The Top Five Most Promising Advances in Celiac Disease

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Is This the Beginning of the End for Celiac Disease? The Top Five Most Promising Advances in Celiac Disease
Are we at the beginning of the end for celiac disease? The last few years have seen numerous advances in celiac diagnosis and treatment. People diagnosed recently and in the future face a very different world than that faced by celiacs just five or ten years ago. In the old days, the process of properly […]
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A Case of Refractory Celiac Disease Cured By Fecal Microbiota Transfer

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A Case of Refractory Celiac Disease Cured By Fecal Microbiota Transfer
In September 2016, the article “Serendipity in Refractory Celiac Disease: Full Recovery of Duodenal Villi and Clinical Symptoms after Fecal Microbiota Transfer” was published in the Journal of Gastrointestinal and Liver Disease describing the first known case of refractory celiac disease cured by a fecal transplant.  The patient in that case was being treated for […]
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New Blood Test May Change the Way We Diagnose Celiac Disease

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New Blood Test May Change the Way We Diagnose Celiac Disease
Doctors attempting to diagnose celiac disease are often confronted by patients who have already given up gluten. For such patients, diagnostic guidelines currently call for a gluten challenge of at least 14 days, followed by duodenal biopsy. There isn’t much good data on how many false-positive results are generate by this method. To get a […]
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Can Cheap, Reliable Gluten Tests Change the World of Celiac Disease?

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Can Cheap, Reliable Gluten Tests Change the World of Celiac Disease?
Can a tiny Virginia start-up change the world with a cheap, reliable devise to test food for gluten on the fly? With their startup called Altede, Ed and Anna Champion, together with business partner Briana Petruzzi, hope to build quick, cheap tests for all sorts of food allergens. Their first target is gluten. Altede is […]
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